Tömegspektrometria alkalmazása a fehérjék vizsgálatában

Translated title of the contribution: Application of mass spectrometry in proteomics

Király Márton, Dalmadiné Kiss Borbála, L. Drahos, K. Vékey, I. Antal, K. Ludányi

Research output: Contribution to journalArticle

Abstract

Mass spectrometry is a high sensitivity, highly selective, high throughput analytical technique. It is well suited to characterize polar, high mass molecules. It is one of the prime analytical techniques to study proteins, to determine their molecular mass, their amino acid sequence and their post-translational modifications. The objective of the present article is to introduce the most important mass spectrometry based methods relevant for protein analysis, like ionization techniques, mass analyzers and tandem mass spectrometry. We shall also introduce "top-down" and "buttomup" protein sequencing and protein quantitation as well.

Translated title of the contributionApplication of mass spectrometry in proteomics
Original languageHungarian
Pages (from-to)61-67
Number of pages7
JournalActa Pharmaceutica Hungarica
Volume86
Issue number2
Publication statusPublished - 2016

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmaceutical Science

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