Application of droplet size analysis for the determination of the required HLB of lemon oil in O/W emulsion

N. A. Niczinger, N. Kállai-Szabó, J. Dredán, L. Budai, M. Hajdú, I. Antal

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Hydrophile-lipophile balance method is one of the requirements which can complete the existing guidelines, thereby making the most stable emulsion. The aim of present work was to determine the required hydrophile-lipophile balance of lemon essential oil in oil-in-water emulsions. Paraffin oil and its known required hydrophile-lipophile balance were used as a standard. Span 80 and Tween 80 or Gelucire 44/14 blend were applied as emulsifying agents. Emulsions were evaluated by droplet size distribution and turbidity measurements. Based on the estimated stability of emulsion series and according to the droplet size analysis with lower variations, the required hydrophile-lipophile balance of lemon oil was measured approximately 12 in oil-in-water systems.

Original languageEnglish
Pages (from-to)11-15
Number of pages5
JournalCurrent Pharmaceutical Analysis
Volume11
Issue number1
Publication statusPublished - Jan 1 2015

Fingerprint

Emulsions
Oils
Emulsifying Agents
Water
Polysorbates
Turbidity
Volatile Oils
Guidelines
lemon oil

Keywords

  • Droplet size distribution
  • Oil-in-water emulsion
  • Paraffin oil standard
  • Required HLB
  • Surface active agents
  • Turbidity

ASJC Scopus subject areas

  • Pharmaceutical Science
  • Molecular Medicine
  • Biochemistry
  • Biophysics

Cite this

Application of droplet size analysis for the determination of the required HLB of lemon oil in O/W emulsion. / Niczinger, N. A.; Kállai-Szabó, N.; Dredán, J.; Budai, L.; Hajdú, M.; Antal, I.

In: Current Pharmaceutical Analysis, Vol. 11, No. 1, 01.01.2015, p. 11-15.

Research output: Contribution to journalArticle

Niczinger, NA, Kállai-Szabó, N, Dredán, J, Budai, L, Hajdú, M & Antal, I 2015, 'Application of droplet size analysis for the determination of the required HLB of lemon oil in O/W emulsion', Current Pharmaceutical Analysis, vol. 11, no. 1, pp. 11-15.
Niczinger, N. A. ; Kállai-Szabó, N. ; Dredán, J. ; Budai, L. ; Hajdú, M. ; Antal, I. / Application of droplet size analysis for the determination of the required HLB of lemon oil in O/W emulsion. In: Current Pharmaceutical Analysis. 2015 ; Vol. 11, No. 1. pp. 11-15.
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