Számítógépes képanalízis alkalmazása gyógyszeres pelletek jellemzésére

Translated title of the contribution: Application of computer image analysis for characterization of pellets

Balogh Emese, Kállai Nikolett, Dredán Judit, Lengyel Miléna, I. Klebovich, I. Antal

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The morphological characteristics of pellets are critical parameters, because of their physico-chemical features depend on the size, shape and surface geometric of the particles. To ensure the spherical shape and required particle of pharmaceutical pellets size is a prerequisite. The detailed technology is basic requirement for the successful and cost efficient production of particles of acceptable quality. Since the determination of the particle size is influenced by the particle shape, therefore microscopic examination is always suggested, which together with image analysis is suitable for the assesment of the most typical parameters. The method of the microscopic image analysis is useful not only for particle size measurement, but also for particle shape and texture evaluation, with a high sensitivity. Using the microscopic method particle shape may be defined either qualitatively and quantitatively. Reviewing the related articles and results on the investigation of sugar pellets demonstrate that roundness characterization is strongly influenced by the applied statistical shape parameters.

Original languageHungarian
Pages (from-to)123-131
Number of pages9
JournalActa Pharmaceutica Hungarica
Volume77
Issue number2
Publication statusPublished - 2007

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Particle Size
Technology
Costs and Cost Analysis
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Számítógépes képanalízis alkalmazása gyógyszeres pelletek jellemzésére. / Emese, Balogh; Nikolett, Kállai; Judit, Dredán; Miléna, Lengyel; Klebovich, I.; Antal, I.

In: Acta Pharmaceutica Hungarica, Vol. 77, No. 2, 2007, p. 123-131.

Research output: Contribution to journalArticle

Emese, Balogh ; Nikolett, Kállai ; Judit, Dredán ; Miléna, Lengyel ; Klebovich, I. ; Antal, I. / Számítógépes képanalízis alkalmazása gyógyszeres pelletek jellemzésére. In: Acta Pharmaceutica Hungarica. 2007 ; Vol. 77, No. 2. pp. 123-131.
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