Application of a system suitability test for quality assurance and performance optimisation of a gas chromatographic system for pesticide residue analysis

Eugenia Soboleva, A. Ámbrus

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

In pesticide residue analysis, screening for over 150 compounds has to be performed on a daily basis. As part of the quality control measures it is crucial to verify that the chromatographic system fits the purpose, or if any deterioration occurred during its previous use. The operation conditions of the chromatographic system can be best monitored with properly selected system suitability test (SST) mixtures, which provide information with one injection on the characteristic performance parameters of the whole system from the injector to the detectors. We developed SST mixtures that are also suitable for use with electron-capture, nitrogen-phosphorus and pulse flame photometric detectors. These SST mixtures were applied over 3 years to monitor the system performance parameters, such as the number of effective theoretical plates, resolution, asymmetry, detection limit and selectivity. The applicability and advantages of these tests are illustrated and discussed.

Original languageEnglish
Pages (from-to)55-65
Number of pages11
JournalJournal of Chromatography A
Volume1027
Issue number1-2
DOIs
Publication statusPublished - Feb 20 2004

Fingerprint

Pesticide Residues
Quality assurance
Quality Control
Phosphorus
Limit of Detection
Nitrogen
Gases
Electrons
Injections
Detectors
Quality control
Deterioration
Screening

Keywords

  • Detection, GC
  • Multiresidue methods
  • Pesticides
  • Quality assurance
  • System suitability test

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

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