Application of a Ball Milling Technique for the Condensation of Anthranilic Hydrazides with Aromatic Aldehydes Towards 4-Quinazolinone Derivatives

T. Magyar, F. Miklós, L. Lázár, F. Fülöp

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6 Citations (Scopus)


An environmentally friendly method was applied to prepare anthranilic hydrazones and quinazolin-4(1H)-ones from anthranilic hydrazides and a number of aldehydes in solventless medium. The condensations proceeded smoothly under ball milling conditions at room temperature, and the products were obtained in high purity and yield.

Original languageEnglish
Pages (from-to)1463-1469
Number of pages7
JournalChemistry of Heterocyclic Compounds
Issue number10
Publication statusPublished - Jan 22 2015



  • ball milling reactions
  • hydrazides
  • mechanochemistry
  • quinazolinones
  • solventless reactions

ASJC Scopus subject areas

  • Organic Chemistry

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