Application of γ-Valerolactone as an Alternative Biomass-Based Medium for Aminocarbonylation Reactions

Diána Marosvölgyi-Haskó, Blanka Lengyel, József M. Tukacs, L. Kollár, László T. Mika

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

γ-Valerolactone (GVL) was proposed as a renewable, nontoxic reaction medium with negligible vapor pressure for homogeneous Pd-catalyzed aminocarbonylation reactions. Iodobenzene as a model substrate and its 4-substituted derivatives were converted to the corresponding 2-ketocarboxamides with high conversions and chemoselectivities in γ-valerolactone. The effect of carbon monoxide pressure and reaction temperature on the conversion and selectivities were studied in the range 1–50 bar and 25–100 °C, respectively. The highest conversion and selectivity was achieved at 25 bar and 50 °C for iodobenzene in GVL for 24 h.

Original languageEnglish
Pages (from-to)1224-1229
Number of pages6
JournalChemPlusChem
Volume81
Issue number11
DOIs
Publication statusPublished - Nov 1 2016

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Biomass
Carbon Monoxide
Vapor pressure
Derivatives
Substrates
Temperature
iodobenzene

Keywords

  • carbonylation
  • green solvents
  • homogeneous catalysis
  • γ-valerolactone

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Application of γ-Valerolactone as an Alternative Biomass-Based Medium for Aminocarbonylation Reactions. / Marosvölgyi-Haskó, Diána; Lengyel, Blanka; Tukacs, József M.; Kollár, L.; Mika, László T.

In: ChemPlusChem, Vol. 81, No. 11, 01.11.2016, p. 1224-1229.

Research output: Contribution to journalArticle

Marosvölgyi-Haskó, Diána ; Lengyel, Blanka ; Tukacs, József M. ; Kollár, L. ; Mika, László T. / Application of γ-Valerolactone as an Alternative Biomass-Based Medium for Aminocarbonylation Reactions. In: ChemPlusChem. 2016 ; Vol. 81, No. 11. pp. 1224-1229.
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