Application of γ-Valerolactone as an Alternative Biomass-Based Medium for Aminocarbonylation Reactions

Diána Marosvölgyi-Haskó, Blanka Lengyel, József M. Tukacs, L. Kollár, László T. Mika

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25 Citations (Scopus)

Abstract

γ-Valerolactone (GVL) was proposed as a renewable, nontoxic reaction medium with negligible vapor pressure for homogeneous Pd-catalyzed aminocarbonylation reactions. Iodobenzene as a model substrate and its 4-substituted derivatives were converted to the corresponding 2-ketocarboxamides with high conversions and chemoselectivities in γ-valerolactone. The effect of carbon monoxide pressure and reaction temperature on the conversion and selectivities were studied in the range 1–50 bar and 25–100 °C, respectively. The highest conversion and selectivity was achieved at 25 bar and 50 °C for iodobenzene in GVL for 24 h.

Original languageEnglish
Pages (from-to)1224-1229
Number of pages6
JournalChemPlusChem
Volume81
Issue number11
DOIs
Publication statusPublished - Nov 1 2016

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Keywords

  • carbonylation
  • green solvents
  • homogeneous catalysis
  • γ-valerolactone

ASJC Scopus subject areas

  • Chemistry(all)

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