Apoptosis az immunfolyamatok regulációjában és az autoimmun betegségek patogenezisében.

Translated title of the contribution: Apoptosis in the regulation of immune processes and in the pathogenesis of autoimmune diseases

Research output: Contribution to journalArticle

Abstract

Programmed cell death (mainly apoptosis) is involved in all fundamental processes of the immune system. Furthermore, apoptosis is essential for elimination of autoreactive lymphocytes and is, therefore a mechanism to guarantee self-tolerance. There are several genes directly implicated in the regulation of lymphoid apoptosis. However, certain mouse strains expressing the defective mutants of those genes exhibit immunological dysfunctions resembling human autoimmune disease conditions. Thus, further analyses of such animal models could facilitate the better understanding of immunopathological abnormalities developing in humans.

Original languageHungarian
Pages (from-to)1315-1320
Number of pages6
JournalOrvosi Hetilap
Volume138
Issue number21
Publication statusPublished - May 25 1997

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Autoimmune Diseases
Apoptosis
Immune System Phenomena
Self Tolerance
Genes
Cell Death
Animal Models
Lymphocytes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Apoptosis az immunfolyamatok regulációjában és az autoimmun betegségek patogenezisében. / Müzes, G.; Igaz, P.

In: Orvosi Hetilap, Vol. 138, No. 21, 25.05.1997, p. 1315-1320.

Research output: Contribution to journalArticle

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