Inhibition by 1 aminoadamantane derivatives of the reproduction of the influenza A (H2N2) Singapore (1) 57 and parainfluenza 1 (Sendai) viruses in chicken chorioallantoic membrane has been investigated. N methylene aryl derivatives proved less effective than 1 aminoadamantane hydrochloride. The antiviral activity of the former compounds depends on the substituting aryl radical. The thioglycollate of 1 aminoadamantane was found to be as active as, and its mercaptopropionate slightly more active than, the hydrochloride.
|Number of pages||7|
|Journal||Acta microbiologica Academiae Scientiarum Hungaricae|
|Publication status||Published - Dec 1 1973|
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