Antiviral effect of 1 aminoadamantane derivatives in vitro

L. Vaczi, O. H. Hankovszky, K. Hideg, G. Hadhazy

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Inhibition by 1 aminoadamantane derivatives of the reproduction of the influenza A (H2N2) Singapore (1) 57 and parainfluenza 1 (Sendai) viruses in chicken chorioallantoic membrane has been investigated. N methylene aryl derivatives proved less effective than 1 aminoadamantane hydrochloride. The antiviral activity of the former compounds depends on the substituting aryl radical. The thioglycollate of 1 aminoadamantane was found to be as active as, and its mercaptopropionate slightly more active than, the hydrochloride.

Original languageEnglish
Pages (from-to)241-247
Number of pages7
JournalActa microbiologica Academiae Scientiarum Hungaricae
Volume20
Issue number3
Publication statusPublished - Dec 1 1973

    Fingerprint

ASJC Scopus subject areas

  • Medicine(all)

Cite this