Antiviral effect of 1 aminoadamantane derivatives in vitro

L. Vaczi, O. H. Hankovszky, K. Hideg, G. Hadhazy

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Inhibition by 1 aminoadamantane derivatives of the reproduction of the influenza A (H2N2) Singapore (1) 57 and parainfluenza 1 (Sendai) viruses in chicken chorioallantoic membrane has been investigated. N methylene aryl derivatives proved less effective than 1 aminoadamantane hydrochloride. The antiviral activity of the former compounds depends on the substituting aryl radical. The thioglycollate of 1 aminoadamantane was found to be as active as, and its mercaptopropionate slightly more active than, the hydrochloride.

Original languageEnglish
Pages (from-to)241-247
Number of pages7
JournalActa Microbiologica Academiae Scientiarum Hungaricae
Volume20
Issue number3
Publication statusPublished - 1973

Fingerprint

Amantadine
Antiviral Agents
Thioglycolates
Chorioallantoic Membrane
Sendai virus
Paramyxoviridae Infections
Singapore
Human Influenza
Reproduction
Chickens
In Vitro Techniques

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Antiviral effect of 1 aminoadamantane derivatives in vitro. / Vaczi, L.; Hankovszky, O. H.; Hideg, K.; Hadhazy, G.

In: Acta Microbiologica Academiae Scientiarum Hungaricae, Vol. 20, No. 3, 1973, p. 241-247.

Research output: Contribution to journalArticle

Vaczi, L. ; Hankovszky, O. H. ; Hideg, K. ; Hadhazy, G. / Antiviral effect of 1 aminoadamantane derivatives in vitro. In: Acta Microbiologica Academiae Scientiarum Hungaricae. 1973 ; Vol. 20, No. 3. pp. 241-247.
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