Antiviral activity of tiazofurine against barley stripe mosaic virus

P. D. Nagy, R. Gáborjányi, L. Kovács, I. Farkas

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Tiazofurine (2-β-D-ribofuranosylthiazole-4-carboxamide) was found to inhibit replication of barley stripe mosaic virus (BSMV) in barley and wheat plants. Treatment with this nucleoside analogue delayed and inhibited symptom development and suppressed virus multiplication. The most effective concentration applied twice as a foliar spray 3 h and one day after inoculation, was 10-3 M. Decreased virus multiplication was obtained without marked phytotoxicity. Three weeks after treatment the antiviral effect declined.

Original languageEnglish
Pages (from-to)41-45
Number of pages5
JournalAntiviral Research
Volume11
Issue number1
DOIs
Publication statusPublished - Feb 1989

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Keywords

  • Barley stripe mosaic virus
  • Plant virus
  • Tiazofurine

ASJC Scopus subject areas

  • Pharmacology
  • Virology

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