Antiretroviral effects of nonderivatized C60 in vitro

J. Nacsa, J. Segesdi, Á Gyuris, T. Braun, H. Rausch, Á Buvári-Barcza, L. Barcza, J. Minarovits, J. Molnár

Research output: Contribution to journalArticle

9 Citations (Scopus)


We have observed that nondenvatized C60 (buckminsterfullerene) could inhibit the replication of simian immunodeficiency virus (SIV) in vitro and the activity of Moloney murine leukemia virus (M-MuLV) reverse transcriptase (RT) (IC50≈ 3 μm). This means that biological effects are exerted via a direct and active interaction of the C60 skeleton with other macromolecules.

Original languageEnglish
Pages (from-to)969-976
Number of pages8
JournalFullerene Science and Technology
Issue number5
Publication statusPublished - Jan 1 1997

ASJC Scopus subject areas

  • Chemical Engineering(all)

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