Antioxidant properties of Myrtilli folium, Phaseoli fructus sine semnibus and drug mixture extracts

M. Then, K. Szentmihályi, A. Gere, Sz Jasztrab, E. Szőke

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In vitro investigations for the antioxidant and free radical scavenging activity of Myrtilli folium-, Phaseoli fructus sine seminibus- and a drug mixture (Equiseti herba, Myrtilli folium, Phaseoli fructus sine seminibus, Urticae folium) extracts showed antioxidant (LPO inhibitory and chain-breaking antioxidant) activity and tree radical (superoxide anion and hydroxyl radical) scavenging effect. The extracts inhibited lipid peroxidation induced enzymatically by adding NADPH and non-enzymatically by adding Fe2+ in brain microsomes and in brain homogenates, respectively. The extracts reduced the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH), which showed chain-breaking antioxidant activity. The extracts scavenged superoxide radicals (O2-•) by inhibiting the reduction of nitro blue tetrazolium evoked by phenazine methosulphate. In addition, the extracts inhibited Fenton-reagent (Fe2+ and H2O2) induced deoxyribose degradation, therefore, it was concluded that the extracts have hydroxyl radical (OH•) scavenging property.

Original languageEnglish
Pages (from-to)169-176
Number of pages8
JournalActa Alimentaria
Volume34
Issue number2
DOIs
Publication statusPublished - Jun 2005

Fingerprint

Antioxidants
Superoxides
antioxidants
drugs
extracts
Pharmaceutical Preparations
Hydroxyl Radical
Free Radicals
Methylphenazonium Methosulfate
hydroxyl radicals
Deoxyribose
superoxide anion
Brain
Microsomes
antioxidant activity
NADP
phenazines
iron
Lipid Peroxidation
Urtica

Keywords

  • Antioxidant and free radical scavenging activity (in vitro)
  • Myrtilli folium
  • Phaseoli fructus sine seminibus

ASJC Scopus subject areas

  • Food Science
  • Medicine (miscellaneous)

Cite this

Antioxidant properties of Myrtilli folium, Phaseoli fructus sine semnibus and drug mixture extracts. / Then, M.; Szentmihályi, K.; Gere, A.; Jasztrab, Sz; Szőke, E.

In: Acta Alimentaria, Vol. 34, No. 2, 06.2005, p. 169-176.

Research output: Contribution to journalArticle

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