Antimicrobial and immunomodulating effects of some phenolic glycosides

J. Molnar, G. Gunics, I. Mucsi, M. Koltai, I. Petri, Y. Shoyama, M. Matsumoto, I. Nishioka

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Several phenolic glycosides, i.e. acteoside, desrhamnosyl acteoside, and purpureaside A, B and C, exerted weak antibacterial effects on Escherichia coli. Acteoside had antiplasmid effects, including F'lac plasmid elimination, and inhibited kanamycin resistance transfer in E. coli. Acteoside, desrhamnosyl acteoside and purpureaside A displayed antiviral effect on Aujeszky virus. All of the phenolic glycosides decreased some human leucocyte functions, including rosette formation, mitogen-induced blast transformation and phagocytic activity in vitro. The purpureaside C had significant proinflammatory action, however, other phenolic glycosides showed neither proinflammatory nor antiinflammatory effect on carrageenin-induced inflammation in vivo.

Original languageEnglish
Pages (from-to)425-432
Number of pages8
JournalActa microbiologica Hungarica
Volume36
Issue number4
Publication statusPublished - Dec 1 1989

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

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    Molnar, J., Gunics, G., Mucsi, I., Koltai, M., Petri, I., Shoyama, Y., Matsumoto, M., & Nishioka, I. (1989). Antimicrobial and immunomodulating effects of some phenolic glycosides. Acta microbiologica Hungarica, 36(4), 425-432.