Antimicrobial and antiplasmid activities of essential oils

Zsuzsanna Schelz, Joseph Molnar, Judit Hohmann

Research output: Contribution to journalArticle

262 Citations (Scopus)


The antimicrobial and antiplasmid activities of essential oils (orange oil, eucalyptus oil, fennel oil, geranium oil, juniper oil, peppermint oil, rosemary oil, purified turpentine oil, thyme oil, Australian tea tree oil) and of menthol, the main component of peppermint oil, were investigated. The antimicrobial activities were determined on the Gram (+) Staphylococcus epidermidis and the Gram (-) Escherichia coli F'lac K12 LE140, and on two yeast Saccharomyces cerevisiae 0425 δ/1 and 0425 52C strains. The antiplasmid activities were investigated on E. coli F'lac bacterial strain. Each of the oils exhibited antimicrobial activity and three of them antiplasmid action. The interaction of peppermint oil and menthol with the antibiotics was studied on the same bacterial strain with the checkerboard method. Peppermint oil and menthol displayed additive synergy with oxytetracycline. A new mechanism of plasmid curing was established for one of the oil components.

Original languageEnglish
Pages (from-to)279-285
Number of pages7
Issue number4
Publication statusPublished - Jun 1 2006


  • Antibiotic resistance
  • Essential oils
  • Menthol
  • Plasmid elimination

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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