Antihypertensive effect of the calcium antagonist isradipine and lipid profile

C. Farsang, I. Kiss, J. Kapocsi, E. Török, E. Maklári

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The hypothesis that plasma lipids may modulate the antihypertensive effect of the calcium antagonist isradipine was tested in 85 patients who had essential hypertension. Significant linear correlations were found between the antihypertensive effect of isradipine and plasma levels of total cholesterol and high-density lipoprotein (HDL2 or HDL3) in normotriglyceridemic (n = 63), but not in hypertriglyceridemic (n = 22), patients. From this, we conclude that normal levels of plasma lipids may modulate the function of calcium channels and their interaction with calcium antagonists.

Original languageEnglish
JournalAmerican Journal of Hypertension
Volume6
Issue number3 PART 2
Publication statusPublished - Mar 1993

Fingerprint

Isradipine
Antihypertensive Agents
Calcium
Lipids
HDL3 Lipoprotein
HDL2 Lipoprotein
Calcium Channels
Cholesterol

Keywords

  • blood pressure
  • Calcium channel
  • isradipine
  • plasma lipids

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Antihypertensive effect of the calcium antagonist isradipine and lipid profile. / Farsang, C.; Kiss, I.; Kapocsi, J.; Török, E.; Maklári, E.

In: American Journal of Hypertension, Vol. 6, No. 3 PART 2, 03.1993.

Research output: Contribution to journalArticle

Farsang, C, Kiss, I, Kapocsi, J, Török, E & Maklári, E 1993, 'Antihypertensive effect of the calcium antagonist isradipine and lipid profile', American Journal of Hypertension, vol. 6, no. 3 PART 2.
Farsang, C. ; Kiss, I. ; Kapocsi, J. ; Török, E. ; Maklári, E. / Antihypertensive effect of the calcium antagonist isradipine and lipid profile. In: American Journal of Hypertension. 1993 ; Vol. 6, No. 3 PART 2.
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