Antifungal diterpenoids and flavonoids from Ballota inaequidens

Gülçin Saltan Çitoǧlu, Betül Sever, Sándor Antus, Eszter Baitz-Gács, Nurten Altanlar

Research output: Contribution to journalArticle

22 Citations (Scopus)


Two diterpenoids (hispanolone 1, ballonigrine 2) and six flavonoids (5-hydroxy-3,7,4′-trimethoxyflavone 3, retusin 4, 5-hydroxy-7,4′- dimethoxyflavone 5, pachypodol 6, 5-hydroxy-3,6,7,4′-tetramethoxyflavone 7, 5-hydroxy-7,3′,4′-trimethoxyflavone 8) have been isolated from the aerial parts of Ballota inaequidens Hub.-Mor. & Patzak. Among them, 7 has not been reported previously in the genus Ballota. The antibacterial and antifungal activities of 1-4, 6, and 8 were tested against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Candida albicans, and Candida crusei.

Original languageEnglish
Pages (from-to)659-663
Number of pages5
JournalPharmaceutical Biology
Issue number8
Publication statusPublished - Dec 1 2004



  • 5-hydroxy- 3,7,4′-trimethoxyflavone
  • 5-hydroxy-3,6,7,4′- tetramethoxyflavone
  • 5-hydroxy-7,3,4′-trimethoxyflavone
  • 5-hydroxy-7,4′-dimethoxyflavone
  • Antifungal activity
  • Ballonigrine
  • Ballota inaequidens
  • Hispanolone
  • Pachypodol
  • Retusin

ASJC Scopus subject areas

  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine

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