Antifungal activity of extracellular hydrolases produced by autolysing Aspergillus nidulans cultures

Melinda Szilágyi, Fruzsina Anton, Katalin Forgács, Jae Hyuk Yu, István Pócsi, Tamás Emri

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Carbon-starving Aspergillus nidulans cultures produce high activities of versatile hydrolytic enzymes and, among these, ChiB endochitinase and EngA β-1,3-endoglucanase showed significant antifungal activity against various fungal species. Double deletion of engA and chiB diminished the antifungal activity of the fermentation broths and increased conidiogenesis and long-term viability of A. nidulans, but decreased the growth rate on culture media containing weak carbon sources. Production of ChiB and EngA can influence fungal communities either directly due to their antifungal properties or indirectly through their effects on vegetative growth. Our data suggest saprophytic fungi as promising future candidates to develop novel biocontrol technologies.

Original languageEnglish
Pages (from-to)849-854
Number of pages6
JournalJournal of Microbiology
Volume50
Issue number5
DOIs
Publication statusPublished - Nov 12 2012

Keywords

  • A. nidulans
  • antifungal activity
  • chitinase
  • proteinase
  • β-1,3-glucanase

ASJC Scopus subject areas

  • Microbiology
  • Applied Microbiology and Biotechnology

Fingerprint Dive into the research topics of 'Antifungal activity of extracellular hydrolases produced by autolysing Aspergillus nidulans cultures'. Together they form a unique fingerprint.

  • Cite this