A quetiapin XR antidepresszív hatása unipoláris major depresszióban

A korai hatáskezdet és az alvásjavító hatás szerepe az öngyilkossá gi kockázat csökkentésében

Translated title of the contribution: Antidepressive efficacy of quetiapine XR in unipolar major depression - The role of early onset of action and sleep-improving effect in decreasing suicide risk

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Although the possibilities of antidepressive pharmacotherapy are continuously improving, the rate of nonresponders or partial responders is still relatively high. Suicidal behaviour, the most tragic consequence of untreated or unsuccessfully treated depression, commonly develops in the first few weeks of antidepressive treatment before the onset of therapeutic action and is strongly related to certain specific symptoms of depression like anxiety, agitation and insomnia. The present paper reviews the newly discovered and well-documented antidepressive effect of quetiapine in bipolar and unipolar depression with special regards to its early onset of action, and its sleep-improving effects. Both beneficial effects play an important role in the reduction of suicidal risk frequently seen in depressed patients.

Original languageHungarian
Pages (from-to)211-215
Number of pages5
JournalNeuropsychopharmacologia Hungarica
Volume11
Issue number4
Publication statusPublished - 2009

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Depressive Disorder
Suicide
Sleep
Depression
Sleep Initiation and Maintenance Disorders
Risk Reduction Behavior
Bipolar Disorder
Anxiety
Drug Therapy
Therapeutics
Quetiapine Fumarate

ASJC Scopus subject areas

  • Neuroscience(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Neuropsychology and Physiological Psychology
  • Clinical Neurology

Cite this

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title = "A quetiapin XR antidepressz{\'i}v hat{\'a}sa unipol{\'a}ris major depresszi{\'o}ban: A korai hat{\'a}skezdet {\'e}s az alv{\'a}sjav{\'i}t{\'o} hat{\'a}s szerepe az {\"o}ngyilkoss{\'a} gi kock{\'a}zat cs{\"o}kkent{\'e}s{\'e}ben",
abstract = "Although the possibilities of antidepressive pharmacotherapy are continuously improving, the rate of nonresponders or partial responders is still relatively high. Suicidal behaviour, the most tragic consequence of untreated or unsuccessfully treated depression, commonly develops in the first few weeks of antidepressive treatment before the onset of therapeutic action and is strongly related to certain specific symptoms of depression like anxiety, agitation and insomnia. The present paper reviews the newly discovered and well-documented antidepressive effect of quetiapine in bipolar and unipolar depression with special regards to its early onset of action, and its sleep-improving effects. Both beneficial effects play an important role in the reduction of suicidal risk frequently seen in depressed patients.",
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