Hirudinnal végzett alvadásgátlás heparin kiváltotta thrombocytopeniában harmadik szívmutét során.

Translated title of the contribution: Anticoagulation with hirudin for repeat cardiac surgery in a patient with heparin induced thrombocytopaenia

Katalin Herman, Miklós Vaszily, Lajos Szentgyörgyi, Eva Ajzner, László Muszbek, Arpád Péterffy

Research output: Contribution to journalArticle

Abstract

The authors present the case of a patient with heparin induced thrombocytopaenia who needed anticoagulation during the perioperative period of a third repeat cardiac operation without transfusions. Prostacyclin pretreatment was contraindicated because of critical aortic stenosis, heparinoids could not have been used due to necessity of postoperative anticoagulation. Recombinant hirudin was applied and its effect was monitored with ekarin coagulation time. Hirudin anticoagulation was continued until the proper INR was reached in the postoperative period. There were no intra- and postoperative complications detected, and there was no need for transfusion either. On his long-term follow-up, 6.5 years after the last cardiac surgery the patients was feeling well and had no complaints. CONCLUSION: Open heart operation of a patient with heparin induced thrombocythopenia can be performed safely by total anticoagulation with lepirudin if it is conducted by ecarin clotting time.

Original languageHungarian
Pages (from-to)67-70
Number of pages4
JournalMagyar sebészet
Volume61 Suppl
DOIs
Publication statusPublished - 2008

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Hirudins
Reoperation
Thoracic Surgery
Heparin
Heparinoids
Perioperative Period
International Normalized Ratio
Aortic Valve Stenosis
Intraoperative Complications
Epoprostenol
Postoperative Period
Emotions

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hirudinnal végzett alvadásgátlás heparin kiváltotta thrombocytopeniában harmadik szívmutét során. / Herman, Katalin; Vaszily, Miklós; Szentgyörgyi, Lajos; Ajzner, Eva; Muszbek, László; Péterffy, Arpád.

In: Magyar sebészet, Vol. 61 Suppl, 2008, p. 67-70.

Research output: Contribution to journalArticle

Herman, Katalin ; Vaszily, Miklós ; Szentgyörgyi, Lajos ; Ajzner, Eva ; Muszbek, László ; Péterffy, Arpád. / Hirudinnal végzett alvadásgátlás heparin kiváltotta thrombocytopeniában harmadik szívmutét során. In: Magyar sebészet. 2008 ; Vol. 61 Suppl. pp. 67-70.
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