Antitestmediált sejtspecifikus vérképzorendszeri autoimmun betegségek

Translated title of the contribution: Antibody-mediated cell-specific hematopoietic autoimmune disorders

Research output: Contribution to journalArticle

Abstract

Although it is clear that immunologic mechanisms play a significant role in the pathophysiology of many hematologic diseases, there are relative few situations where it is possible to gain a detailed understanding of immune damage in vivo in humans. Autoimmune hemolytic anemia, immune thrombocytopenia and immune neutropenia as antibody-mediated cell-specific disorders are of particular interest in this regard. Autoimmune hemolytic anemia represents a group of disorders in which individuals produce antibodies directed toward one or more of their own erythrocyte membrane antigens. This leads to destruction of the antibody-coated crythrocytes. The pathophysiology of the decreased erythrocyte survival has been examined with increasing sophistication for many years. This paper first discusses the underlying mechanisms responsible for autoimmune hemolytic anemias then consider immune thrombocytopenia and immune neutropenia.

Original languageHungarian
Pages (from-to)39-42
Number of pages4
JournalOrvosi Hetilap
Volume148
Issue numberSUPPL. 1
DOIs
Publication statusPublished - Apr 8 2007

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Autoimmune Hemolytic Anemia
Idiopathic Thrombocytopenic Purpura
Neutropenia
Antibodies
Erythrocyte Aging
Hematologic Diseases
Erythrocyte Membrane
Antigens

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Antitestmediált sejtspecifikus vérképzorendszeri autoimmun betegségek. / Pálóczi, K.

In: Orvosi Hetilap, Vol. 148, No. SUPPL. 1, 08.04.2007, p. 39-42.

Research output: Contribution to journalArticle

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