The recent development of antibacterial fluoroquinolone derivatives, as an important result of drug research has been reviewed. In this first part of the survey aspects of medicinal chemistry, particularly the structure-properties-activity relationships are summarized. The authors give a general picture of the physical-chemical properties, the mechanism of action, the pharmacokinetic parameters characterizing for this group. The review is made current by the fact that the number of antibacterial fluoroquinolone drugs available in Hungary rose up to three last year.
|Number of pages||7|
|Publication status||Published - Jan 1 1991|
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