Antibacterial fluoroquinolones. I. Medicinal chemistry

K. Takacs-Novak, T. Gabor, M. Takacs

Research output: Contribution to journalReview article

Abstract

The recent development of antibacterial fluoroquinolone derivatives, as an important result of drug research has been reviewed. In this first part of the survey aspects of medicinal chemistry, particularly the structure-properties-activity relationships are summarized. The authors give a general picture of the physical-chemical properties, the mechanism of action, the pharmacokinetic parameters characterizing for this group. The review is made current by the fact that the number of antibacterial fluoroquinolone drugs available in Hungary rose up to three last year.

Original languageEnglish
Pages (from-to)279-285
Number of pages7
JournalGyogyszereszet
Volume35
Issue number6
Publication statusPublished - Jan 1 1991

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ASJC Scopus subject areas

  • Pharmacology

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