Antibacterial effect, plasmid curing activity and chemical structure of some tricyclic compounds

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Diethazine, amitriptyline and imipramine showed bacteriostatic and bactericidal effect on different bacteria. Chlorpromazine sulphoxide and fluorescein were ineffective even at 1000 μg/ml. The antibacterial compounds deleted at 40-70% frequency the F'lac plasmid of Escherichia coli K12 LE-140.

Original languageEnglish
Pages (from-to)1-6
Number of pages6
JournalActa Microbiologica Academiae Scientiarum Hungaricae
Volume24
Issue number1
Publication statusPublished - 1977

Fingerprint

F Factor
Escherichia coli K12
Amitriptyline
Imipramine
Fluorescein
Plasmids
Bacteria
diethazine
opromazine

ASJC Scopus subject areas

  • Medicine(all)

Cite this

@article{de9d14a55a47465e8eda44be96076701,
title = "Antibacterial effect, plasmid curing activity and chemical structure of some tricyclic compounds",
abstract = "Diethazine, amitriptyline and imipramine showed bacteriostatic and bactericidal effect on different bacteria. Chlorpromazine sulphoxide and fluorescein were ineffective even at 1000 μg/ml. The antibacterial compounds deleted at 40-70{\%} frequency the F'lac plasmid of Escherichia coli K12 LE-140.",
author = "J. Moln{\'a}r and Y. M{\'a}ndi and Holland, {I. B.} and G. Schneider",
year = "1977",
language = "English",
volume = "24",
pages = "1--6",
journal = "Acta Microbiologica et Immunologica Hungarica",
issn = "1217-8950",
publisher = "Akademiai Kiado",
number = "1",

}

TY - JOUR

T1 - Antibacterial effect, plasmid curing activity and chemical structure of some tricyclic compounds

AU - Molnár, J.

AU - Mándi, Y.

AU - Holland, I. B.

AU - Schneider, G.

PY - 1977

Y1 - 1977

N2 - Diethazine, amitriptyline and imipramine showed bacteriostatic and bactericidal effect on different bacteria. Chlorpromazine sulphoxide and fluorescein were ineffective even at 1000 μg/ml. The antibacterial compounds deleted at 40-70% frequency the F'lac plasmid of Escherichia coli K12 LE-140.

AB - Diethazine, amitriptyline and imipramine showed bacteriostatic and bactericidal effect on different bacteria. Chlorpromazine sulphoxide and fluorescein were ineffective even at 1000 μg/ml. The antibacterial compounds deleted at 40-70% frequency the F'lac plasmid of Escherichia coli K12 LE-140.

UR - http://www.scopus.com/inward/record.url?scp=0017683139&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017683139&partnerID=8YFLogxK

M3 - Article

C2 - 22219

AN - SCOPUS:0017683139

VL - 24

SP - 1

EP - 6

JO - Acta Microbiologica et Immunologica Hungarica

JF - Acta Microbiologica et Immunologica Hungarica

SN - 1217-8950

IS - 1

ER -