Anti-Inflammatory and Anti-Oxidative Nutrition in Hypoalbuminemic Dialysis Patients (AIONID) study

Results of the pilot-feasibility, double-blind, randomized, placebo-controlled trial

Manoch Rattanasompattikul, M. Molnár, Martin L. Lee, Ramanath Dukkipati, Rachelle Bross, Jennie Jing, Youngmee Kim, Anne C. Voss, Debbie Benner, Usama Feroze, Iain C. MacDougall, John A. Tayek, Keith C. Norris, Joel D. Kopple, Mark Unruh, Csaba P. Kovesdy, Kamyar Kalantar-Zadeh

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Background: Low serum albumin is common and associated with protein-energy wasting, inflammation, and poor outcomes in maintenance hemodialysis (MHD) patients. We hypothesized that in-center (in dialysis clinic) provision of high-protein oral nutrition supplements (ONS) tailored for MHD patients combined with anti-oxidants and anti-inflammatory ingredients with or without an anti-inflammatory appetite stimulator (pentoxifylline, PTX) is well tolerated and can improve serum albumin concentration. Methods: Between January 2008 and June 2010, 84 adult hypoalbuminemic (albumin

Original languageEnglish
Pages (from-to)247-257
Number of pages11
JournalJournal of Cachexia, Sarcopenia and Muscle
Volume4
Issue number4
DOIs
Publication statusPublished - Dec 2013

Fingerprint

Serum Albumin
Renal Dialysis
Dialysis
Anti-Inflammatory Agents
Randomized Controlled Trials
Placebos
Pentoxifylline
Appetite
Oxidants
Albumins
Proteins
Maintenance
Inflammation

Keywords

  • Albumin
  • Anti-inflammatory ingredients
  • Anti-oxidant ingredients
  • Hemodialysis
  • Hypoalbuminemia
  • Inflammation
  • Oral nutrition supplements
  • Protein intake

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physiology (medical)

Cite this

Anti-Inflammatory and Anti-Oxidative Nutrition in Hypoalbuminemic Dialysis Patients (AIONID) study : Results of the pilot-feasibility, double-blind, randomized, placebo-controlled trial. / Rattanasompattikul, Manoch; Molnár, M.; Lee, Martin L.; Dukkipati, Ramanath; Bross, Rachelle; Jing, Jennie; Kim, Youngmee; Voss, Anne C.; Benner, Debbie; Feroze, Usama; MacDougall, Iain C.; Tayek, John A.; Norris, Keith C.; Kopple, Joel D.; Unruh, Mark; Kovesdy, Csaba P.; Kalantar-Zadeh, Kamyar.

In: Journal of Cachexia, Sarcopenia and Muscle, Vol. 4, No. 4, 12.2013, p. 247-257.

Research output: Contribution to journalArticle

Rattanasompattikul, M, Molnár, M, Lee, ML, Dukkipati, R, Bross, R, Jing, J, Kim, Y, Voss, AC, Benner, D, Feroze, U, MacDougall, IC, Tayek, JA, Norris, KC, Kopple, JD, Unruh, M, Kovesdy, CP & Kalantar-Zadeh, K 2013, 'Anti-Inflammatory and Anti-Oxidative Nutrition in Hypoalbuminemic Dialysis Patients (AIONID) study: Results of the pilot-feasibility, double-blind, randomized, placebo-controlled trial', Journal of Cachexia, Sarcopenia and Muscle, vol. 4, no. 4, pp. 247-257. https://doi.org/10.1007/s13539-013-0115-9
Rattanasompattikul, Manoch ; Molnár, M. ; Lee, Martin L. ; Dukkipati, Ramanath ; Bross, Rachelle ; Jing, Jennie ; Kim, Youngmee ; Voss, Anne C. ; Benner, Debbie ; Feroze, Usama ; MacDougall, Iain C. ; Tayek, John A. ; Norris, Keith C. ; Kopple, Joel D. ; Unruh, Mark ; Kovesdy, Csaba P. ; Kalantar-Zadeh, Kamyar. / Anti-Inflammatory and Anti-Oxidative Nutrition in Hypoalbuminemic Dialysis Patients (AIONID) study : Results of the pilot-feasibility, double-blind, randomized, placebo-controlled trial. In: Journal of Cachexia, Sarcopenia and Muscle. 2013 ; Vol. 4, No. 4. pp. 247-257.
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AU - Norris, Keith C.

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AU - Kalantar-Zadeh, Kamyar

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