Anti glutamate-decarboxylase antibodies: A liaison between localisation related epilepsy, stiff-person syndrome and type-1 diabetes mellitus

Anna Szucs, Gábor Barcs, Gábor Winkler, Zsuzsanna Soós, András Folyovich, Anna Kelemen, Péter Várallyay, Anita Kamondi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We present two patients with partial epilepsy, type-1 diabetes and stiff person syndrome associated with high serum autoantibody levels to glutamate-decarboxylase (anti-GAD). Both patients were or have suffered from additional autoimmune conditions. The presence of stiff person syndrome and elevated anti-GAD levels have to make clinicians look for additional autoimmune conditions including type-1 diabetes. On the other hand, the co-morbidity of partial epilepsy with autoimmune conditions in patients with elevated serum anti-GAD suggests an autoimmune mechanism of partial epilepsy in these cases.

Original languageEnglish
Pages (from-to)269-271
Number of pages3
JournalIdeggyogyaszati szemle
Volume67
Issue number7-8
Publication statusPublished - Jul 30 2014

Keywords

  • Anti-GAD
  • Autoimmune epilepsy
  • Stiff person's

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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