Answer to the "Comment on functional consequences of Kv1.3 ion channel rearrangement into the immunological synapse" by Stefan Bittner et al. [Immunol. Lett. 125 (Aug 15 (2)) (2009) 156-157]

Péter Hajdú, Orsolya Szilágyi, Ágnes Tóth, Zoltán Krasznai, Krisztina Pocsai, György Panyi

Research output: Contribution to journalLetter


A critical comment to our paper on Kv1.3 channels in the immunological synapse (IS) was published, which emphasized the role of two-pore potassium channels (TASK-1 and 3) in the physiology of T lymphocytes [1]. Here we provide several lines of evidence that presence of TASK channels in the T cell line (a murine Th2 Cell line, D10) used in our experimental model cannot explain the changes in the biophysical parameters of the whole-cell current upon formation of an IS [2].

Original languageEnglish
Pages (from-to)47-49
Number of pages3
JournalImmunology letters
Issue number1
Publication statusPublished - Mar 10 2010



  • Immunological synapse
  • Kv1.3
  • TASK channels

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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