Angiotensin II stimulates phosphatidylinositol turnover in adrenal glomerulosa cells by a calcium-independent mechanism

L. Hunyady, Tamás Balla, A. Spät

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Angiotensin II enhances phosphatidylinositol turnover in isolated adrenal glomerulosa cells. In the present experiments we examined whether this effect required the presence of extracellular Ca2+. It was found that neither the stimulation of phosphatidylinositol breakdown nor the stimulation of incorporation of [32P]phosphate into phosphatidic acid and phosphatidylinositol required the presence of extracellular Ca2+. These observations suggest that the enhancement of phosphatidylinositol turnover may precede, but does not depend on, angiotensin-induced Ca2+ influx.

Original languageEnglish
Pages (from-to)133-135
Number of pages3
JournalBiochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism
Volume753
Issue number1
DOIs
Publication statusPublished - Aug 29 1983

Fingerprint

Zona Glomerulosa
Phosphatidylinositols
Angiotensin II
Calcium
Phosphatidic Acids
Angiotensins
Phosphates
Experiments

Keywords

  • (Rat adrenal glomerulosa cell)
  • Angiotensin II
  • Ca influx
  • Phosphatidylinositol
  • Phospholipid turnover

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Endocrinology

Cite this

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AU - Balla, Tamás

AU - Spät, A.

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AB - Angiotensin II enhances phosphatidylinositol turnover in isolated adrenal glomerulosa cells. In the present experiments we examined whether this effect required the presence of extracellular Ca2+. It was found that neither the stimulation of phosphatidylinositol breakdown nor the stimulation of incorporation of [32P]phosphate into phosphatidic acid and phosphatidylinositol required the presence of extracellular Ca2+. These observations suggest that the enhancement of phosphatidylinositol turnover may precede, but does not depend on, angiotensin-induced Ca2+ influx.

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