In summary, angiogenesis, the formation of new blood vessels, is important in leukocyte extravasation and thus the pathogenesis of RA. The outcome of neovascularization highly depends on the imbalance between angiogenic and angiostatic mediators produced in the rheumatoid synovium. Therefore, angiogenesis research is important for the understanding of the pathogenesis of inflammatory arthritis. In addition, existing and potential angiostatic drugs may be useful for future therapy of RA.
|Number of pages||15|
|Journal||Journal of Investigative Medicine|
|Publication status||Published - Feb 1998|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)