Analysis of the genotoxic activities of 5 compounds affecting insect fertility

J. Szabad, Blanka Bennettová

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

The genotoxicity of 5 compounds that affect insect fertility were tested by means of the 'Drosophila wing mosaic assay'. Larvae heterozygous for recessive marker mutations were fed with the food containing the test compound for a few days, and after they had developed to adults their wings were screened for clones of wing cells exhibiting the phenotype of recessive marker mutations. 6-Azauridine, dimilin and methoprene showed no activity. Actinomycin C displayed a low level of genotoxicity, while HMPA was a very potent mutagen.

Original languageEnglish
Pages (from-to)197-200
Number of pages4
JournalMutation Research Letters
Volume173
Issue number3
DOIs
Publication statusPublished - 1986

Fingerprint

Fertility
Insects
Azauridine
Diflubenzuron
Methoprene
Hempa
Mutation
Mutagens
Drosophila
Larva
Clone Cells
Phenotype
Food
Assays
cactinomycin

ASJC Scopus subject areas

  • Genetics
  • Toxicology
  • Medicine(all)

Cite this

Analysis of the genotoxic activities of 5 compounds affecting insect fertility. / Szabad, J.; Bennettová, Blanka.

In: Mutation Research Letters, Vol. 173, No. 3, 1986, p. 197-200.

Research output: Contribution to journalArticle

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