Analysis of cyanobacterial toxins (anatoxin-a, cylindrospermopsin, microcystin-LR) by capillary electrophoresis

Gábor Vasas, Attila Gáspár, Csilla Páger, Gyula Surányi, Csaba Máthé, Márta M. Hamvas, George Borbely

Research output: Contribution to journalArticle

64 Citations (Scopus)


Capillary zone electrophoresis (CZE) and micellar electrokinetic chromatography (MEKC) were applied to the simultaneous separation of cyanobacterial toxins (anatoxin-a, microcystin-LR, cylindrospermopsin). The analytical performance data of both methods, optimized for the three toxins, were similar with a precision of migration times smaller than 0.8 RSD% and a detection limit in the range of 1-4 μg/mL, using spectrophotometric detection at 230 nm. Both methods were applied to an analysis of cyanotoxins in water bloom samples and crude cyanobacterial extracts. The results obtained indicate that, for complex matrices, the sequential application of CZE and MEKC is necessary. It is recommended to use both CE techniques for the analysis of the same sample in order to confirm the results by an orthogonal approach.

Original languageEnglish
Pages (from-to)108-115
Number of pages8
Issue number1
Publication statusPublished - Jan 1 2004


  • Anatoxin-a
  • Capillary electrophoresis
  • Cyanobacterial toxins
  • Cylindrospermopsin
  • Microcystin-LR

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry

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