Myastheniás betegek altatása thymectomia során.

Translated title of the contribution: Anaesthesia of the myasthenic patients during thymectomy

Judit Hallay, Csaba Micskei, Sándor Kollár, Sándor Sz Kiss, B. Fülesdi

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Myasthenia is a rare autoimmune disease characterized by fluctuating muscle weakness and fatigability due to a reduction in available acetylcholine receptors at the neuromuscular junction. Data of 186 patients suffering from myasthenia were collected retrospectively. All patients underwent thymectomy over a 23 years period from 1981 to 2006 without surgical mortality. Postoperative ventilation was required for more than 24 hours in seven patients and one patient needed postoperative ventilatory support more than seven days. Thymectomy for myasthenia was performed using promethazine and atropine in general anaesthesia. Introduction could be facilitated with propofol, etomidate or thiopental and sevoflurane, avoiding use of any muscle relaxants. Non-depolarizing muscle relaxants were not used during the procedures. Adequate surgical conditions were provided by short-acting inhaled anaesthetics (sevoflurane) and small doses of opiates. 95% of the narcotized patients were immediately extubated after the procedure in the operating room. Length of stay in intensive care unit could have been reduced without any postoperative ventilatory support. Nonsteroid analgesics and nalbuphine were used for pain relief. Anaesthesia of thymectomy is based on volatile gases. Airway complications can be prevented with use of small amounts of anticholinergic drugs, perhaps steroids.

Original languageHungarian
Pages (from-to)37-40
Number of pages4
JournalMagyar sebészet
Volume61 Suppl
DOIs
Publication statusPublished - 2008

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Thymectomy
Muscle Weakness
Anesthesia
Opiate Alkaloids
Neuromuscular Nondepolarizing Agents
Nalbuphine
Etomidate
Promethazine
Thiopental
Neuromuscular Junction
Cholinergic Antagonists
Cholinergic Receptors
Propofol
Operating Rooms
Rare Diseases
Atropine
General Anesthesia
Autoimmune Diseases
Intensive Care Units
Ventilation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Myastheniás betegek altatása thymectomia során. / Hallay, Judit; Micskei, Csaba; Kollár, Sándor; Sz Kiss, Sándor; Fülesdi, B.

In: Magyar sebészet, Vol. 61 Suppl, 2008, p. 37-40.

Research output: Contribution to journalArticle

Hallay, J, Micskei, C, Kollár, S, Sz Kiss, S & Fülesdi, B 2008, 'Myastheniás betegek altatása thymectomia során.', Magyar sebészet, vol. 61 Suppl, pp. 37-40. https://doi.org/10.1556/MaSeb.61.2008.Suppl.9
Hallay, Judit ; Micskei, Csaba ; Kollár, Sándor ; Sz Kiss, Sándor ; Fülesdi, B. / Myastheniás betegek altatása thymectomia során. In: Magyar sebészet. 2008 ; Vol. 61 Suppl. pp. 37-40.
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