An unusual association: Anti-Jo1 and anti-SRP antibodies in the serum of a patient with polymyositis

Melinda Vincze, Peter A. Molnár, Judit Tumpek, Lászlóné Szőllősi, Ágnes Gyetvai, Anikó Kapitány, Katalin Dankó

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16 Citations (Scopus)

Abstract

The idiopathic inflammatory myopathies are systemic autoimmune diseases characterized by chronic inflammation, resulting in the progressive weakness of the proximal muscles. Myositis-specific or myositis-associated autoantibodies can often be found in serum of polymyositis and dermatomyositis patients. This autoantibody presence may play a significant role in patient diagnosis and classification. We present a female polymyositis patient characterized with serious muscle weakness and lung involvement. Anti-Jo1 antibodies were detected in the patient's serum at the time of diagnosis. After 5 years of treatment and surveillance, recent laboratory analysis showed the presence anti-SRP antibody in her serum.

Original languageEnglish
Pages (from-to)811-814
Number of pages4
JournalClinical rheumatology
Volume29
Issue number7
DOIs
Publication statusPublished - Jul 2010

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Keywords

  • Anti-SRP
  • Anti-jo-1
  • Interstitial lung disease
  • Polymyositis

ASJC Scopus subject areas

  • Rheumatology

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