An NMR approach for the determination of the substitution pattern in mono-modified cyclodextrins

Peter Forgo, Valerian T. D'Souza

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

One of the problems in cyclodextrin chemistry is the unequivocal determination of structures of systems under investigation. A simple procedure that can be used for the determination of the position of the substitution in these systems is presented here. The main requirement of this procedure is that the proton attached to the substituted carbon has a magnetic environment that is different from other likely sites of attachment.

Original languageEnglish
Pages (from-to)8533-8537
Number of pages5
JournalTetrahedron Letters
Volume40
Issue number49
DOIs
Publication statusPublished - Dec 3 1999

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Keywords

  • Cyclodextrins
  • HSQC
  • Modified-cyclodextrins
  • NMR
  • Selective long-range INEPT

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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