An expedient route to p-tert-butylthiacalix[4]arene 1,3-diethers via Mitsunobu reactions

I. Bitter, Viktor Csokai

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Regioselective distal dialkylation of p-tert-butylthiacalix[4]arene with alcohols was performed under the Mitsunobu protocol using the DEAD/TPP system. The method provides a versatile tool for obtaining 1,3-diethers with different functional groups in the alkyl chains.

Original languageEnglish
Pages (from-to)2261-2265
Number of pages5
JournalTetrahedron Letters
Volume44
Issue number11
DOIs
Publication statusPublished - Mar 10 2003

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Functional groups
Alcohols
p-tert-butylthiacalix(4)arene

Keywords

  • Mitsunobu reaction
  • O-alkylation
  • Thiacalix[4]arenes

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

An expedient route to p-tert-butylthiacalix[4]arene 1,3-diethers via Mitsunobu reactions. / Bitter, I.; Csokai, Viktor.

In: Tetrahedron Letters, Vol. 44, No. 11, 10.03.2003, p. 2261-2265.

Research output: Contribution to journalArticle

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