An expedient route to p-tert-butylthiacalix[4]arene 1,3-diethers via Mitsunobu reactions

István Bitter, Viktor Csokai

Research output: Contribution to journalArticle

55 Citations (Scopus)

Abstract

Regioselective distal dialkylation of p-tert-butylthiacalix[4]arene with alcohols was performed under the Mitsunobu protocol using the DEAD/TPP system. The method provides a versatile tool for obtaining 1,3-diethers with different functional groups in the alkyl chains.

Original languageEnglish
Pages (from-to)2261-2265
Number of pages5
JournalTetrahedron Letters
Volume44
Issue number11
DOIs
Publication statusPublished - Mar 10 2003

Keywords

  • Mitsunobu reaction
  • O-alkylation
  • Thiacalix[4]arenes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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