An efficient synthesis of optically active 2-[4-(6-chloro-2- quinoxalinyloxy)-phenoxy]-propionamide derivatives

József Kövér, József Tompa, S. Antus, Tamás Gunda

Research output: Contribution to journalArticle

Abstract

An efficient synthesis of (R)-(+)-2-[4-(6-chloro-2-quinoxalinyloxy)- phenoxy]-propion-amide 4a-e is described by simple amidation of Quizalofop-methyl® [(R)-(+)-3]. The reduced susceptibility of quinoxalinyl moiety of (R)-(+)-3 toward nucleophilic reagents was discussed on the basis of QM calculation.

Original languageEnglish
Pages (from-to)403-406
Number of pages4
JournalHeterocyclic Communications
Volume11
Issue number5
Publication statusPublished - 2005

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Diethylpropion
Amides
Derivatives
propionamide
quizalofop

ASJC Scopus subject areas

  • Organic Chemistry

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An efficient synthesis of optically active 2-[4-(6-chloro-2- quinoxalinyloxy)-phenoxy]-propionamide derivatives. / Kövér, József; Tompa, József; Antus, S.; Gunda, Tamás.

In: Heterocyclic Communications, Vol. 11, No. 5, 2005, p. 403-406.

Research output: Contribution to journalArticle

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