Condensation of ethyl 3-azido-4-oxopentanoate, easily accessible from ethyl 3-chloro-4-oxopentanoate, with primary amines was found to produce ethyl 4-imino-3-amino-2-pentenoates. In addition, ethyl 4-imino-3-amino-2-pentenoates were reduced chemoselectively to the corresponding ethyl 4-alkylamino-3-amino-2- pentenoates upon hydrogenation.
|Number of pages||8|
|Publication status||Published - Sep 12 2005|
- Functionalized enamino esters
- Functionalized ketimines
- γ-amino esters
ASJC Scopus subject areas
- Organic Chemistry