An Efficient One-Pot Four-Component Synthesis of 9-Aryl-Hexahydroacridine-1,8-Dione Derivatives in the Presence of a Molecular Sieves Supported Iron Catalyst

Ágnes Magyar, Z. Hell

Research output: Contribution to journalArticle

Abstract

Abstract: A series of 9-aryl-hexahydroacridine-1,8-diones are synthetized with good to excellent yields (50–99%) via a one-pot four-component reaction of dimedone, aromatic aldehydes and ammonium acetate in the presence of 4 Å molecular sieves modified with iron(III) as an efficient heterogeneous catalyst, in ethanol. The process offers the advantages of high yields, mild reaction conditions and easy work-up procedure. The catalyst can be reused without significant loss of activity.

Original languageEnglish
JournalCatalysis Letters
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

Molecular sieves
Iron
Derivatives
Catalysts
Aldehydes
Ethanol
dimedone
ammonium acetate

Keywords

  • 4 Å Molecular sieves
  • 9-Aryl-hexahydro-acridine-1,8-dione
  • Heterogeneous catalysis
  • Iron
  • Multicomponent reactions

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

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abstract = "Abstract: A series of 9-aryl-hexahydroacridine-1,8-diones are synthetized with good to excellent yields (50–99{\%}) via a one-pot four-component reaction of dimedone, aromatic aldehydes and ammonium acetate in the presence of 4 {\AA} molecular sieves modified with iron(III) as an efficient heterogeneous catalyst, in ethanol. The process offers the advantages of high yields, mild reaction conditions and easy work-up procedure. The catalyst can be reused without significant loss of activity.",
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AU - Hell, Z.

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N2 - Abstract: A series of 9-aryl-hexahydroacridine-1,8-diones are synthetized with good to excellent yields (50–99%) via a one-pot four-component reaction of dimedone, aromatic aldehydes and ammonium acetate in the presence of 4 Å molecular sieves modified with iron(III) as an efficient heterogeneous catalyst, in ethanol. The process offers the advantages of high yields, mild reaction conditions and easy work-up procedure. The catalyst can be reused without significant loss of activity.

AB - Abstract: A series of 9-aryl-hexahydroacridine-1,8-diones are synthetized with good to excellent yields (50–99%) via a one-pot four-component reaction of dimedone, aromatic aldehydes and ammonium acetate in the presence of 4 Å molecular sieves modified with iron(III) as an efficient heterogeneous catalyst, in ethanol. The process offers the advantages of high yields, mild reaction conditions and easy work-up procedure. The catalyst can be reused without significant loss of activity.

KW - 4 Å Molecular sieves

KW - 9-Aryl-hexahydro-acridine-1,8-dione

KW - Heterogeneous catalysis

KW - Iron

KW - Multicomponent reactions

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