An Efficient One-Pot Four-Component Synthesis of 9-Aryl-Hexahydroacridine-1,8-Dione Derivatives in the Presence of a Molecular Sieves Supported Iron Catalyst

Ágnes Magyar, Zoltán Hell

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Abstract: A series of 9-aryl-hexahydroacridine-1,8-diones are synthetized with good to excellent yields (50–99%) via a one-pot four-component reaction of dimedone, aromatic aldehydes and ammonium acetate in the presence of 4 Å molecular sieves modified with iron(III) as an efficient heterogeneous catalyst, in ethanol. The process offers the advantages of high yields, mild reaction conditions and easy work-up procedure. The catalyst can be reused without significant loss of activity. Graphic Abstract: [Figure not available: see fulltext.].

Original languageEnglish
Pages (from-to)2528-2534
Number of pages7
JournalCatalysis Letters
Issue number9
Publication statusPublished - Sep 1 2019



  • 4 Å Molecular sieves
  • 9-Aryl-hexahydro-acridine-1,8-dione
  • Heterogeneous catalysis
  • Iron
  • Multicomponent reactions

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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