Amphiphilic hyperbranched polyglycerols in a new role as highly efficient multifunctional surface active stabilizers for poly(lactic/glycolic acid) nanoparticles

György Kasza, Gergo Gyulai, Ágnes Ábrahám, Györgyi Szarka, Béla Iván, E. Kiss

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Amphiphilic hyperbranched polyglycerols (HbPG) were synthesized by dodecyl and octadecyl alcohols as direct initiators for the ring-opening multibranching polymerization of glycidol. These polymers possess molecular weight dependent surface activity, and are efficient surfactants and stabilizers for poly(lactic/glycolic acid) (PLGA) nanoparticles, opening new possibilities for functionalized drug carriers, targeting, imaging agents, etc.

Original languageEnglish
Pages (from-to)4348-4352
Number of pages5
JournalRSC Advances
Volume7
Issue number8
DOIs
Publication statusPublished - 2017

Fingerprint

glycidol
glycolic acid
Stabilizers (agents)
Drug Carriers
Ring opening polymerization
Lactic acid
Surface-Active Agents
Polymers
Alcohols
Surface active agents
Molecular weight
Nanoparticles
Imaging techniques
polyglycerol

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Amphiphilic hyperbranched polyglycerols in a new role as highly efficient multifunctional surface active stabilizers for poly(lactic/glycolic acid) nanoparticles. / Kasza, György; Gyulai, Gergo; Ábrahám, Ágnes; Szarka, Györgyi; Iván, Béla; Kiss, E.

In: RSC Advances, Vol. 7, No. 8, 2017, p. 4348-4352.

Research output: Contribution to journalArticle

Kasza, György ; Gyulai, Gergo ; Ábrahám, Ágnes ; Szarka, Györgyi ; Iván, Béla ; Kiss, E. / Amphiphilic hyperbranched polyglycerols in a new role as highly efficient multifunctional surface active stabilizers for poly(lactic/glycolic acid) nanoparticles. In: RSC Advances. 2017 ; Vol. 7, No. 8. pp. 4348-4352.
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