Amorfizálás a gyógyszer-technológiában

Translated title of the contribution: Amorphization in pharmaceutical technology

P. Szabó-Révész, Orsolya Laczkovich, I. Erös

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The amorphization of crystalline active ingredients may be necessary because of the polymorphism of the active substance, the poor water-solubility of the drug material, difficult processing in the crystalline form and the taking out of a patent for a new (amorphous) form. This article introduces protocols for amorphization, which use methods traditionally applied in pharmaceutical technology. The protocols involve three possible routes: solvent methods, hot-melt technologies and milling procedures. With this presentation, the authors suggest help for practising experts to find the correct amorphization method.

Original languageHungarian
Pages (from-to)39-44
Number of pages6
JournalActa Pharmaceutica Hungarica
Volume74
Issue number1
Publication statusPublished - 2004

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Pharmaceutical Technology
Solubility
Technology
Water
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Pharmaceutical Science

Cite this

Amorfizálás a gyógyszer-technológiában. / Szabó-Révész, P.; Laczkovich, Orsolya; Erös, I.

In: Acta Pharmaceutica Hungarica, Vol. 74, No. 1, 2004, p. 39-44.

Research output: Contribution to journalArticle

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