Amniotic fluid shake test versus lecithin-sphingomyelin ratio in the antenatal prediction of respiratory distress syndrome

I. M. Szabo, I. F. Csaba, I. A. Drozgyik, P. F. Novak

Research output: Contribution to journalArticle


Surfactant content of 211 amniotic fluid samples taken between 28 and 42 wk gestations was determined by the shake test. Parallel with this also the lecithin/sphingomyelin (L/S) ratio was measured in 99 cases. When the test was positive no respiratory distress syndrome (RDS) occurred, while 25 RDS (53.34%) developed in 46 newborns with negative test and 8 RDS (15.38%) in 52 newborns with an intermediate test result. RDS was observed in all cases when the L/S ratio was below 1.5. At L/S ratios between 1.5 and 2.0, RDS appeared in 50% of the negative tests and 20% of the intermediate tests. However, when the L/S ratio was over 2.0 no RDS occurred even in the case of negative tests. For the clinical analysis the positive test gives exact information; no RDS is to be expected in such cases. In the case of a negative test, however, the authors think it is necessary also to determine the L/S ratio.

Original languageEnglish
Pages (from-to)260-263
Number of pages4
JournalZeitschrift fur Geburtshilfe und Perinatologie
Issue number4
Publication statusPublished - Dec 1 1977


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynaecology

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