The maternal and fetal risks of genetic amniocentesis are described and discussed. The 14th to the 20th wk of pregnancy is stated to be the best time for this investigation. Numerous reports in the literature indicate that with appropriate care and experience, the technique is almost without risk. Although the number of amniocentesis procedures carried out in early pregnancy is decidedly less than those peformed in the last 10 wk, it appears that the risk of damage is not more than 1 to 2%. Maternal complications mentioned are, haematoma of the uterine wall, infection, damage to the bladder and bowel, maternal sensitisation and fetomaternal bleeding. Fetal complications are damage to the vessels on the fetal side of the placenta, rarely damage to the fetus, spontaneous abortion, and the possibility that developmental abnormalities might be caused. It is to be desired that the method might be so simplified as to permit routine use without risk.
|Translated title of the contribution||Amniocentesis for prenatal diagnosis of genetic defects|
|Number of pages||6|
|Publication status||Published - Jan 1 1975|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health