Amino acid distribution in immature rat brain

M. Banay-Schwartz, T. DeGuzman, A. Lajtha, M. Palkovits

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We compared the levels of amino acids in the free pool in 6 regions (cerebral cortex, olfactory bulb, substantia nigra, globus pallidus, caudate nucleus, and spinal cord) in the newborn rat brain. The amino acid distribution was heterogeneous, with the area of highest concentration containing 2-3 fold as much as the lowest area. These differences were considerably less than those previously found for adult brain. Although some areas omen contained high levels of amino acids, and others mostly low levels, the distribution of the various amino acids was highly variable. This heterogeneity of distribution in the newborn brain was different from that in the adult brain. We conclude that there is significant heterogeneity of amino acid distribution, that it is different for each amino acid, and that it undergoes major changes during development.

Original languageEnglish
Pages (from-to)393-403
Number of pages11
JournalNEUROBIOLOGY
Volume4
Issue number4
Publication statusPublished - Dec 1 1996

Keywords

  • Amino acid level heterogeneity
  • Cerebral amino acids
  • Developmental changes in brain
  • Newborn brain regions
  • Regional distribution of amino acids

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Amino acid distribution in immature rat brain'. Together they form a unique fingerprint.

  • Cite this

    Banay-Schwartz, M., DeGuzman, T., Lajtha, A., & Palkovits, M. (1996). Amino acid distribution in immature rat brain. NEUROBIOLOGY, 4(4), 393-403.