Amino acid concentrations in cerebrospinal fluid of patients with multiple sclerosis

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

As oligodendrocytes have binding sites for excitatory amino acids (glutamate, aspartate, serine, etc.), a role of these molecules in demyelinating disorders is possible. We measured the levels of amino acids in the cerebrospinal fluid (CSF) of patients with multiple sclerosis in comparison with CSF obtained by myelography from patients with lower back pain. There were no significant differences in the CSF concentrations of these amino acids between the two groups. Normal concentrations of excitotoxins do not exclude the role of these molecules in demyelinating disorders.

Original languageEnglish
Pages (from-to)96-98
Number of pages3
JournalActa Neurologica Scandinavica
Volume95
Issue number2
Publication statusPublished - 1997

Fingerprint

Multiple Sclerosis
Cerebrospinal Fluid
Demyelinating Diseases
Amino Acids
Myelography
Excitatory Amino Acids
Oligodendroglia
Neurotoxins
Low Back Pain
Aspartic Acid
Serine
Glutamic Acid
Binding Sites

Keywords

  • amino acid
  • cerebrospinal fluid
  • multiple sclerosis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Amino acid concentrations in cerebrospinal fluid of patients with multiple sclerosis. / Klivényi, P.; Kékesi, K.; Juhész, G.; Vécsei, L.

In: Acta Neurologica Scandinavica, Vol. 95, No. 2, 1997, p. 96-98.

Research output: Contribution to journalArticle

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