Alveolaris csontregeneráció serkentése thrombocyta-dús plasma és Cerasorb-graft kombinációjával Beagle kutyákban (Szövettani és hisztomorfometriai vizsgálatok).

Translated title of the contribution: Alveolar bone regeneration stimulated by a combination of platelet-rich plasma and Cerasorb graft in Beagle dogs. Histological and histomorphometric studies

Zsuzsanna Suba, Dániel Takács, Szabolcs Gyulai-Gaál, Katalin Kovács, Norbert Velich, Krisztián Szigeti, György Szabó

Research output: Contribution to journalArticle


Healing of extraction wounds was examined in an animal experiment model on Beagle dogs. After bilateral extraction of the premolars of 12 dogs the alveoli were filled up with a combination of beta-tricalcium phosphate (Cerasorb) graft and platelet rich plasma (PRP) on the experimental side, and with Cerasorb alone on the control side. Biopsy specimens were taken from the regenerating bone at 6, 12 and 24 weeks after surgery for histological study. Results of the histologic and histomorphometric examinations revealed that after 6 weeks the newly formed bone was significantly denser on the experimental side. After 12 weeks this difference became moderate, and after 24 weeks the bone forming activity was nearly equal on the two sides. These results suggest that local administration of Cerasorb and PRP results in more intense bone regeneration, especially in the early phase.

Original languageHungarian
Pages (from-to)143-149
Number of pages7
JournalFogorvosi szemle
Issue number4
Publication statusPublished - Aug 2004


ASJC Scopus subject areas

  • Medicine(all)

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