Alveolaris csontregeneráció serkentése thrombocyta-dús plasma és Cerasorb-graft kombinációjával Beagle kutyákban (Szövettani és hisztomorfometriai vizsgálatok).

Translated title of the contribution: Alveolar bone regeneration stimulated by a combination of platelet-rich plasma and Cerasorb graft in Beagle dogs. Histological and histomorphometric studies

Z. Suba, Dániel Takács, Szabolcs Gyulai-Gaál, Katalin Kovács, Norbert Velich, Krisztián Szigeti, György Szabó

Research output: Contribution to journalArticle

Abstract

Healing of extraction wounds was examined in an animal experiment model on Beagle dogs. After bilateral extraction of the premolars of 12 dogs the alveoli were filled up with a combination of beta-tricalcium phosphate (Cerasorb) graft and platelet rich plasma (PRP) on the experimental side, and with Cerasorb alone on the control side. Biopsy specimens were taken from the regenerating bone at 6, 12 and 24 weeks after surgery for histological study. Results of the histologic and histomorphometric examinations revealed that after 6 weeks the newly formed bone was significantly denser on the experimental side. After 12 weeks this difference became moderate, and after 24 weeks the bone forming activity was nearly equal on the two sides. These results suggest that local administration of Cerasorb and PRP results in more intense bone regeneration, especially in the early phase.

Original languageHungarian
Pages (from-to)143-149
Number of pages7
JournalFogorvosi szemle
Volume97
Issue number4
Publication statusPublished - 2004

Fingerprint

Bone Regeneration
Platelet-Rich Plasma
Dogs
Transplants
Bone and Bones
Bicuspid
Wound Healing
Animal Models
Biopsy
beta-tricalcium phosphate

Cite this

Alveolaris csontregeneráció serkentése thrombocyta-dús plasma és Cerasorb-graft kombinációjával Beagle kutyákban (Szövettani és hisztomorfometriai vizsgálatok). / Suba, Z.; Takács, Dániel; Gyulai-Gaál, Szabolcs; Kovács, Katalin; Velich, Norbert; Szigeti, Krisztián; Szabó, György.

In: Fogorvosi szemle, Vol. 97, No. 4, 2004, p. 143-149.

Research output: Contribution to journalArticle

Suba, Z. ; Takács, Dániel ; Gyulai-Gaál, Szabolcs ; Kovács, Katalin ; Velich, Norbert ; Szigeti, Krisztián ; Szabó, György. / Alveolaris csontregeneráció serkentése thrombocyta-dús plasma és Cerasorb-graft kombinációjával Beagle kutyákban (Szövettani és hisztomorfometriai vizsgálatok). In: Fogorvosi szemle. 2004 ; Vol. 97, No. 4. pp. 143-149.
@article{12c9930d560e4fcd82a726c40b2dfff3,
title = "Alveolaris csontregener{\'a}ci{\'o} serkent{\'e}se thrombocyta-d{\'u}s plasma {\'e}s Cerasorb-graft kombin{\'a}ci{\'o}j{\'a}val Beagle kuty{\'a}kban (Sz{\"o}vettani {\'e}s hisztomorfometriai vizsg{\'a}latok).",
abstract = "Healing of extraction wounds was examined in an animal experiment model on Beagle dogs. After bilateral extraction of the premolars of 12 dogs the alveoli were filled up with a combination of beta-tricalcium phosphate (Cerasorb) graft and platelet rich plasma (PRP) on the experimental side, and with Cerasorb alone on the control side. Biopsy specimens were taken from the regenerating bone at 6, 12 and 24 weeks after surgery for histological study. Results of the histologic and histomorphometric examinations revealed that after 6 weeks the newly formed bone was significantly denser on the experimental side. After 12 weeks this difference became moderate, and after 24 weeks the bone forming activity was nearly equal on the two sides. These results suggest that local administration of Cerasorb and PRP results in more intense bone regeneration, especially in the early phase.",
author = "Z. Suba and D{\'a}niel Tak{\'a}cs and Szabolcs Gyulai-Ga{\'a}l and Katalin Kov{\'a}cs and Norbert Velich and Kriszti{\'a}n Szigeti and Gy{\"o}rgy Szab{\'o}",
year = "2004",
language = "Hungarian",
volume = "97",
pages = "143--149",
journal = "Fogorvosi szemle",
issn = "0015-5314",
publisher = "Ifjusagi Lapkiado Vallalat",
number = "4",

}

TY - JOUR

T1 - Alveolaris csontregeneráció serkentése thrombocyta-dús plasma és Cerasorb-graft kombinációjával Beagle kutyákban (Szövettani és hisztomorfometriai vizsgálatok).

AU - Suba, Z.

AU - Takács, Dániel

AU - Gyulai-Gaál, Szabolcs

AU - Kovács, Katalin

AU - Velich, Norbert

AU - Szigeti, Krisztián

AU - Szabó, György

PY - 2004

Y1 - 2004

N2 - Healing of extraction wounds was examined in an animal experiment model on Beagle dogs. After bilateral extraction of the premolars of 12 dogs the alveoli were filled up with a combination of beta-tricalcium phosphate (Cerasorb) graft and platelet rich plasma (PRP) on the experimental side, and with Cerasorb alone on the control side. Biopsy specimens were taken from the regenerating bone at 6, 12 and 24 weeks after surgery for histological study. Results of the histologic and histomorphometric examinations revealed that after 6 weeks the newly formed bone was significantly denser on the experimental side. After 12 weeks this difference became moderate, and after 24 weeks the bone forming activity was nearly equal on the two sides. These results suggest that local administration of Cerasorb and PRP results in more intense bone regeneration, especially in the early phase.

AB - Healing of extraction wounds was examined in an animal experiment model on Beagle dogs. After bilateral extraction of the premolars of 12 dogs the alveoli were filled up with a combination of beta-tricalcium phosphate (Cerasorb) graft and platelet rich plasma (PRP) on the experimental side, and with Cerasorb alone on the control side. Biopsy specimens were taken from the regenerating bone at 6, 12 and 24 weeks after surgery for histological study. Results of the histologic and histomorphometric examinations revealed that after 6 weeks the newly formed bone was significantly denser on the experimental side. After 12 weeks this difference became moderate, and after 24 weeks the bone forming activity was nearly equal on the two sides. These results suggest that local administration of Cerasorb and PRP results in more intense bone regeneration, especially in the early phase.

UR - http://www.scopus.com/inward/record.url?scp=16544383750&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=16544383750&partnerID=8YFLogxK

M3 - Article

C2 - 15495539

AN - SCOPUS:16544383750

VL - 97

SP - 143

EP - 149

JO - Fogorvosi szemle

JF - Fogorvosi szemle

SN - 0015-5314

IS - 4

ER -