Alternative conditions for the synthesis of novel spiro[1,3-N,N-heterocyclic-adamantanes]

Ferenc Miklós, Alexandra Petrisor, Ferenc Fülöp

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A series of new spiro[N-heterocyclic-adamantanes] was synthesized through the reaction of 2-adamantanone with β-amino carboxamides. Depending on the chemical and physical characteristics of the starting compounds, the cyclocondensations proceeded under simple and mild (aqueous, solvent-free, ball-milling or/and microwave-assisted) conditions with no necessity for chromatographic purification of the products. The reaction was extended to leucinamide and salicylamide.

Original languageEnglish
Pages (from-to)158-171
Number of pages14
JournalArkivoc
Volume2015
Issue number7
DOIs
Publication statusPublished - Oct 9 2015

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Keywords

  • Aqueous
  • Ballmilling reactions
  • Environmentally friendly methods
  • Mechanochemical
  • Microwave-assisted
  • Solvent-free

ASJC Scopus subject areas

  • Organic Chemistry

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