Altered monocyte functions in patients with angioimmunoblastic lymphadenopathy.

K. Pálóczi, M. Zeher, K. Lukács, M. Kávai, G. Szegedi

Research output: Contribution to journalArticle

Abstract

Monocyte function was investigated in ten patients with angioimmunoblastic lymphadenopathy (AILD). Although spontaneous migration, phagocytosis and opsonisation of monocytes were unimpaired, the chemotactic response and erythrocyte-antibody-rosette (EA-rosette) formation were decreased significantly. The migratory response of normal monocytes was inhibited on preincubation with serum from AILD patients. It is suggested that the immune abnormality in AILD, previously thought to involve T-B and natural killer lymphocytes, extends to the monocyte-macrophage system.

Original languageEnglish
Pages (from-to)109-115
Number of pages7
JournalHaematologia
Volume20
Issue number2
Publication statusPublished - 1987

ASJC Scopus subject areas

  • Hematology

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