Altered filtrability of white blood cells after myocardial infarction.

L. Bogár, J. Mikita, G. B. Nash, M. J. Smith, J. A. Dormandy, M. Tekeres

Research output: Contribution to journalArticle

Abstract

Abnormal white blood cell rheological behaviour has been implicated as a cause of blood flow disturbances under conditions of ischaemia and reduced perfusion pressure. Accordingly, we have tested the mechanical properties of white cells following myocardial infarction by measuring the rate at which suspension of these cells cause plugging of Nuclepore filters. The number of clogging particles in a standard white cell suspension increased by the third day after infarction but subsequently decreased to the control levels. Since white cells can cause blockage of narrow blood vessels, it is assumed that such changes in cellular properties may influence the eventual extent of infarction.

Original languageEnglish
Pages (from-to)207-211
Number of pages5
JournalActa medica Hungarica
Volume46
Issue number2-3
Publication statusPublished - 1989

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Bogár, L., Mikita, J., Nash, G. B., Smith, M. J., Dormandy, J. A., & Tekeres, M. (1989). Altered filtrability of white blood cells after myocardial infarction. Acta medica Hungarica, 46(2-3), 207-211.