Alterations in Dry Mass Content of Collagen Fibers in Degenerative Tendinopathy and Tendon-Rupture

LáSzlo Józsa, Matti Lehto, Martti Kvist, Jozsef B. Bálint, Antal Reffy

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

The dry mass concentration and collagen fiber morphology of intact, as well as of degenerated and ruptured human Achilles, biceps brachii, extensor pollicis longus and quadriceps tendons, were determined by using the interference microscopical technique. The variation in the collagen fiber thickness was demonstrated in different intact tendons, the fibers being largest in the Achilles and smallest in the extensor pollicis longus tendons. However, the intact tendons exhibited only thick collagen fibers. In the degenerative tendinopathies an increase of the dry mass content was observed, being especially marked in calcifying tendinopathy. In the degenerated tendons the average collagen fiber diameter had decreased, and two clearly distinct populations of thick and thin fibers were observed. The dry mass content of the thick fibers was significantly greater than that of the thin fibers. The present results demonstrate striking changes in the collagen and its dry mass content in degenerative tendinopathy, thus also increasing the susceptibility to ruptures.

Original languageEnglish
Pages (from-to)140-146
Number of pages7
JournalMatrix
Volume9
Issue number2
DOIs
Publication statusPublished - Jan 1 1989

    Fingerprint

Keywords

  • collagen dry mass
  • degenerative tendinopathy
  • fiber thickness
  • tendon rupture

ASJC Scopus subject areas

  • Rheumatology

Cite this