Alteration of body composition in rats: Effect of organic chromium and L-carnitine

S. Fekete, I. Szakáll, Emma Kósa, Emese Andrásofszky, Kinga Fodor, A. Hidas, J. Tözsér

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A growth trial was carried out to test the effect of organic, trivalent chromium and L-carnitine on the body composition of growing rats. At the same time, an evaluation of different measurement methods (weight of epididymal fat pad, adipocyte morphometry, total body electrical conductivity) was performed. Outbred Wistar rats of 30 days of age were fed diets of different (0, 10 and 20%) protein level. The diets were supplemented with 4 mg/kg Cr as chromium nicotinate, and 100 mg/kg L-carnitine. The experimental feeding lasted 15 days, after a 5-day-long adjustment period. It was found that Cr addition increased feed intake. Both treatments caused changes in body composition, increasing fat and protein deposition. Organic chromium had no effect at either protein level, while L-carnitine improved the protein retention only at an optimum (20%) protein supply. No statistically significant correlation was found between total body electrical conductivity (TOBEC) and body composition, which could be attributed to the great individual differences. A close correlation was found among total body fat percentage, weight of epididymal fat pad and the adipocyte surface. The data suggest that there is an interaction between dietary protein supply and the effect of repartitioning agents.

Original languageEnglish
Pages (from-to)385-398
Number of pages14
JournalActa veterinaria Hungarica
Volume49
Issue number4
DOIs
Publication statusPublished - Dec 1 2001

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Keywords

  • Adipocyte morphometry
  • Body composition
  • Dietary protein level
  • Epididymal fat pad
  • L-carnitine
  • Net protein ratio (NPR)
  • Nutriceuticals
  • Protein efficiency ratio (PER)
  • Rat
  • Total body electrical conductivity (TOBEC)
  • Trivalent chromium

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Fekete, S., Szakáll, I., Kósa, E., Andrásofszky, E., Fodor, K., Hidas, A., & Tözsér, J. (2001). Alteration of body composition in rats: Effect of organic chromium and L-carnitine. Acta veterinaria Hungarica, 49(4), 385-398. https://doi.org/10.1556/AVet.49.2001.4.3