Alpha and beta adrenergic sensitivity in trained and untrained albino rats

Gábor Pavlik, ágnes Hegyi, Róbert Frenkl

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The effects on the blood pressure and heart rate responses of different adrenergic stimulants (norepinephrine, sympathomim, epinephrine and isoproterenol) and blocking agents (phenoxybenzamine and propranolol) were studied in control (N = 55) and exercising (N = 52) albino rats under anaesthesia. The test rats exercised by regular swimming for 10-14 weeks. Alpha stimulation and beta blocking produced smaller responses while alpha blocking and beta stimulation were followed by greater changes after training as compared with the control animals. The assumption of a modified adrenergic receptor sensitivity could not be substantiated by the results; the observations indicate rather a complex change in the autonomous regulation following regular physical exercise.

Original languageEnglish
Pages (from-to)65-73
Number of pages9
JournalEuropean Journal of Applied Physiology and Occupational Physiology
Volume36
Issue number1
DOIs
Publication statusPublished - Mar 1 1976

Keywords

  • Adrenergic responsivity
  • Blood pressure
  • Heart rate
  • Physical training

ASJC Scopus subject areas

  • Physiology
  • Public Health, Environmental and Occupational Health

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