Agyria-pachygyria and agenesis of the corpus callosum: Autosomal recessive inheritance with neonatal death

László Sztriha, L. Al-Gazali, A. Dawodu, M. Bakir, P. Chandran

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

We report three neonates, one boy and two girls, born to an inbred Arab family who had cortical dysplasia, probably agyriapachygyria, and agenesis of the corpus callosum. All had asphyxia, intractable seizures, and increased muscle tone at birth and died in the neonatal period. Congenital microcephaly or dysmorphic features were absent. Cytogenetic abnormality, metabolic disorder, and intrauterine infection were excluded. These cases suggest a new cerebral dysgenesis syndrome with autosomal recessive inheritance.

Original languageEnglish
Pages (from-to)1466-1469
Number of pages4
JournalNeurology
Volume50
Issue number5
DOIs
Publication statusPublished - May 1998

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Agyria-pachygyria and agenesis of the corpus callosum: Autosomal recessive inheritance with neonatal death'. Together they form a unique fingerprint.

  • Cite this